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1.
Journal of Korean Society of Pediatric Endocrinology ; : 33-43, 2010.
Article in Korean | WPRIM | ID: wpr-132438

ABSTRACT

PURPOSE: We evaluated the effects of treatment with gonadotropin-releasing hormone agonist (GnRHa) on growth and sex hormone changes in idiopathic true precocious puberty girls. METHODS: From January 2003 through May 2007, forty-three female children, who were diagnosed as idiopathic true precocious puberty and were administered GnRHa for one year were enrolled in this retrospective study. We divided the patients into two groups according to midparental height (MPH) minus predicted adult height (PAH) (MPH-PAH > or = 5 cm, or MPH-PAH or = 5 cm), height standard deviation score for bone age (Ht SDS for BA) was significantly increased before and after treatment (-1.8 +/- 0.7 vs. -1.3 +/- 0.8). PAH after treatment was increased to 153.6 +/- 5.8 cm from 149.1 +/- 4.6 cm before treatment (PAH gain 4.5 +/- 4.4 cm). Furthermore, as MPH-PAH increased, so did PAH gain (r = 0.59, P or = 5 cm) before treatment attained significant height gain with GnRHa administration. The successful gonadal suppression was also observed.


Subject(s)
Adult , Child , Female , Humans , Alkaline Phosphatase , Body Mass Index , Breast , Breast Feeding , Gonadal Steroid Hormones , Gonadotropin-Releasing Hormone , Gonads , Phenazines , Puberty, Precocious , Retrospective Studies , Rickets , Vitamin D Deficiency
2.
Journal of Korean Society of Pediatric Endocrinology ; : 33-43, 2010.
Article in Korean | WPRIM | ID: wpr-132435

ABSTRACT

PURPOSE: We evaluated the effects of treatment with gonadotropin-releasing hormone agonist (GnRHa) on growth and sex hormone changes in idiopathic true precocious puberty girls. METHODS: From January 2003 through May 2007, forty-three female children, who were diagnosed as idiopathic true precocious puberty and were administered GnRHa for one year were enrolled in this retrospective study. We divided the patients into two groups according to midparental height (MPH) minus predicted adult height (PAH) (MPH-PAH > or = 5 cm, or MPH-PAH or = 5 cm), height standard deviation score for bone age (Ht SDS for BA) was significantly increased before and after treatment (-1.8 +/- 0.7 vs. -1.3 +/- 0.8). PAH after treatment was increased to 153.6 +/- 5.8 cm from 149.1 +/- 4.6 cm before treatment (PAH gain 4.5 +/- 4.4 cm). Furthermore, as MPH-PAH increased, so did PAH gain (r = 0.59, P or = 5 cm) before treatment attained significant height gain with GnRHa administration. The successful gonadal suppression was also observed.


Subject(s)
Adult , Child , Female , Humans , Alkaline Phosphatase , Body Mass Index , Breast , Breast Feeding , Gonadal Steroid Hormones , Gonadotropin-Releasing Hormone , Gonads , Phenazines , Puberty, Precocious , Retrospective Studies , Rickets , Vitamin D Deficiency
3.
The Journal of the Korean Orthopaedic Association ; : 467-472, 2000.
Article in Korean | WPRIM | ID: wpr-655402

ABSTRACT

In infected uncemented hip arthroplasty, 4 cases which showed well-fixed femoral stem were managed by staged procedure. Thorough debridement, removal of acetabular socket and insertion of antibiotics impregnated cement spacer was done without removal of femoral stem. No recurrence of infection or loosening was developed after staged procedure and revisoin was performed after infection evidence disappeared. The interval between the two procedures was 4 months (3-6) on average. In Weber's criteria, all 4 cases were graded as having definitive cure of infection on both clinical and radiological criteria (Grade I) .


Subject(s)
Acetabulum , Anti-Bacterial Agents , Arthroplasty , Arthroplasty, Replacement, Hip , Debridement , Hip , Recurrence
4.
The Journal of the Korean Orthopaedic Association ; : 257-262, 2000.
Article in Korean | WPRIM | ID: wpr-650681

ABSTRACT

PURPOSE: This study was performed to provide the applicability and safety of predeposited and intraoperative autologous transfusion in patients who underwent lumbar spine fusion surgery. MATERIALS AND METHODS: Materials were 130 patients, consisted of 55 with pure autologous blood, 34 with autologous and homologous blood, and 41 with homologous blood. We analyzed the amount of transfusion, the occurrence of complication during blood transfusion, and the perioperative hematologic changes. RESULTS: One level spinal fusion was possible with only predeposited autologous blood transfusion. On the other hand, homologous blood also was required in addition to the predeposited and intraoperative autotransfusion in more than two level surgery. But homologous blood less than 33-39% of total required blood amount was used compared to the amount used in pure homologous blood group. It took about three months to recover complete blood count into the preoperative state, independent from the predeposited amount and the presence of underlying diseases such as cardiovascular disease, chronic debilitating disease. But faster recovery was shown in male under 30 years old. Even though trivial symptoms such as headache and dizziness were developed during preoperative blood collecting, there was no sign of complication during the transfusion of the predeposited and intraoperative autologous blood. CONCLUSION: One level spinal fusion procedures including posterolateral fusion and posterior lumbar interbody fusion were possible with only predeposited autologous blood transfusion, and additional use of predeposited and intraoperative autotransfusion was an effective and safe method to reduce the use of homologous blood and to avoid complications in case of more than two level spinal fusion.


Subject(s)
Adult , Humans , Male , Blood Cell Count , Blood Transfusion , Blood Transfusion, Autologous , Cardiovascular Diseases , Dizziness , Hand , Headache , Spinal Fusion , Spine
5.
The Journal of the Korean Orthopaedic Association ; : 689-693, 2000.
Article in Korean | WPRIM | ID: wpr-653527

ABSTRACT

PURPOSE: The purpose of this study was to report the clinical result of subtrochanteric fractures which were treated with Rowe plate. MATERIALS AND METHODS: 30 cases of subtrochanteric fracture, which were operatively treated with Rowe plate, were evaluated clinically and radiographically. All patients were followed for at least 1 year. RESULTS: Primary bony union was achieved in 28 cases (93%) . Bony union after secondary operative procedure was obtained in 2 cases (6.7%) . The fracture was united within 6 months except 3 cases. As complications, coxa vara deformity under 120. of neck-shaft angle was observed in 2 cases and one of them was associated with limb shortening more than 1 cm. CONCLUSION: We could obtain satisfactory clinical results with the use of Rowe plate in treating some selected cases of subtrochanteric fracture. The good indications for the use of Rowe plate seem to be some subtrochanteric fracture associated with intertrochanteric fracture, long spiral subtrochanteric fracture, comminuted subtrochanteric fracture with multiple large fragment, and subtrochanteric fracture in deformed proximal femur.


Subject(s)
Humans , Congenital Abnormalities , Coxa Vara , Extremities , Femur , Fractures, Comminuted , Hip Fractures , Surgical Procedures, Operative
6.
Journal of the Korean Knee Society ; : 236-239, 1999.
Article in Korean | WPRIM | ID: wpr-730711

ABSTRACT

Tumoral calcinosis is an uncommon disease, characterized by deposits of large, calcified soft tissue masses around major joints in children and young adults. The causes of the lesion have not yet been established, but are presumed an inborn error of metabolism of phosphorus. It has been recommanded medical treatment or surgical excision, but recurrence of the lesion is frequent. We report a case of young female patient who presented with tumoral calcinosis at the age of 10 years.


Subject(s)
Child , Female , Humans , Young Adult , Calcinosis , Joints , Knee Joint , Knee , Metabolism , Phosphorus , Recurrence
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